The asymmetric distribution of phosphatidylcholine in rat brain synaptic plasma membranes
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چکیده
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Distribution and fluidizing action of soluble and aggregated amyloid beta-peptide in rat synaptic plasma membranes.
The effects of soluble and aggregated amyloid beta-peptide (Abeta) on cortical synaptic plasma membrane (SPM) structure were examined using small angle x-ray diffraction and fluorescence spectroscopy approaches. Electron density profiles generated from the x-ray diffraction data demonstrated that soluble and aggregated Abeta1-40 peptides associated with distinct regions of the SPM. The width of...
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ژورنال
عنوان ژورنال: Neurochemistry International
سال: 1993
ISSN: 0197-0186
DOI: 10.1016/0197-0186(93)90012-t